| Active Players |
| 92 | Adeniyi, Olasunkanmi | OB | 09/12/1997 | 22 | 6' 01" | 248 | Toledo | PIT FA | 18 CFA | 2 |
| 94 | Alualu, Tyson | DE | 05/12/1987 | 32 | 6' 02" | 294 | California | JAX | 10 01 010 | 10 |
| 72 | Banner, Zach | OT | 12/25/1993 | 25 | 6' 08" | 361 | USC | IND | 17 04 137 | 3 |
| 26 | Barron, Mark | SS | 10/27/1989 | 29 | 6' 01" | 213 | Alabama | TB | 12 01 007 | 8 |
| 4 | Berry, Jordan | PT | 03/18/1991 | 28 | 6' 05" | 210 | Eastern Kentucky | PIT FA | 15 SFA | 5 |
| 9 | Boswell, Chris | PK | 03/16/1991 | 28 | 6' 02" | 185 | Rice | HOU FA | 14 CFA | 5 |
| 96 | Buggs, Isaiah | DT | 08/24/1996 | 23 | 6' 03" | 306 | Alabama | PIT | 19 06 192 | R |
| 25 | Burns, Artie | CB | 05/01/1995 | 24 | 6' 00" | 193 | Miami | PIT | 16 01 025 | 4 |
| 55 | Bush Jr., Devin | IB | 07/18/1998 | 21 | 5' 11" | 234 | Michigan | PIT | 19 01 010 | R |
| 57 | Canaday, Kameron | LS | 08/20/1992 | 27 | 6' 04" | 245 | Portland State | ARZ FA | 16 CFA | 3 |
| 56 | Chickillo, Anthony | DE | 12/10/1992 | 26 | 6' 03" | 270 | Miami | PIT | 15 06 212 | 5 |
| 30 | Conner, James | RB | 05/05/1995 | 24 | 6' 01" | 233 | Pittsburgh | PIT | 17 03 105 | 3 |
| 37 | Dangerfield, Jordan | FS | 12/25/1990 | 28 | 5' 11" | 200 | Towson | BUF FA | 13 CFA | 3 |
| 66 | DeCastro, David | OG | 01/11/1990 | 29 | 6' 05" | 310 | Stanford | PIT | 12 01 024 | 8 |
| 48 | Dupree, Bud | DE | 02/12/1993 | 26 | 6' 04" | 269 | Kentucky | PIT | 15 01 022 | 5 |
| 34 | Edmunds, Terrell | FS | 01/20/1997 | 22 | 6' 00" | 217 | Virginia Tech | PIT | 18 01 028 | 2 |
| 51 | Elliott, Jayrone | LB | 11/11/1991 | 27 | 6' 03" | 255 | Toledo | GB FA | 14 CFA | 4 |
| 71 | Feiler, Matt | OT | 07/07/1992 | 27 | 6' 06" | 330 | Bloomsburg | HOU FA | 14 CFA | 3 |
| 67 | Finney, BJ | OC | 10/26/1991 | 27 | 6' 04" | 318 | Kansas State | PIT FA | 15 CFA | 4 |
| 39 | Fitzpatrick, Minkah | FS | 11/17/1996 | 22 | 6' 00" | 204 | Alabama | MIA | 18 01 011 | 2 |
| 73 | Foster, Ramon | OG | 01/07/1986 | 33 | 6' 06" | 325 | Tennessee | PIT FA | 09 CFA | 11 |
| 81 | Gentry, Zach | TE | 09/10/1996 | 23 | 6' 08" | 262 | Michigan | PIT | 19 05 141 | R |
| 54 | Gilbert III, Ulysees | IB | 08/09/1997 | 22 | 6' 00" | 228 | Akron | PIT | 19 06 207 | R |
| 85 | Grimble, Xavier | TE | 09/22/1992 | 27 | 6' 04" | 257 | USC | NYG FA | 14 CFA | 4 |
| 23 | Haden, Joe | CB | 04/14/1989 | 30 | 5' 11" | 193 | Florida | CLE | 10 01 007 | 10 |
| 79 | Hargrave, Javon | DT | 02/07/1993 | 26 | 6' 01" | 309 | South Carolina State | PIT | 16 03 089 | 4 |
| 97 | Heyward, Cameron | DE | 05/06/1989 | 30 | 6' 05" | 294 | Ohio State | PIT | 11 01 031 | 9 |
| 28 | Hilton, Mike | CB | 03/09/1994 | 25 | 5' 09" | 183 | Mississippi | JAX FA | 16 CFA | 3 |
| 6 | Hodges, Devlin | QB | 04/12/1996 | 23 | 6' 01" | 211 | Samford | PIT FA | 19 CFA | R |
| 80 | Holton, Johnny | WR | 08/22/1991 | 28 | 6' 01" | 190 | Cincinnati | OAK FA | 16 CFA | 3 |
| 18 | Johnson, Diontae | WR | 07/05/1996 | 23 | 5' 10" | 183 | Toledo | PIT | 19 03 066 | R |
| 74 | Johnson, Fred | OG | 06/05/1997 | 22 | 6' 07" | 326 | Florida | PIT FA | 19 CFA | R |
| 29 | Kelly, Kameron | CB | 08/19/1996 | 23 | 6' 02" | 204 | San Diego State | DAL FA | 18 CFA | 1 |
| 31 | Layne, Justin | CB | 01/12/1998 | 21 | 6' 02" | 192 | Michigan State | PIT | 19 03 083 | R |
| 44 | Matakevich, Tyler | IB | 12/22/1992 | 26 | 6' 00" | 238 | Temple | PIT | 16 07 246 | 4 |
| 93 | McCullers, Daniel | NT | 08/11/1992 | 27 | 6' 07" | 352 | Tennessee | PIT | 14 06 215 | 6 |
| 89 | McDonald, Vance | TE | 06/13/1990 | 29 | 6' 04" | 267 | Rice | SF | 13 02 055 | 7 |
| 11 | Moncrief, Donte | WR | 08/06/1993 | 26 | 6' 02" | 221 | Mississippi | IND | 14 03 090 | 6 |
| 22 | Nelson, Steven | CB | 01/22/1993 | 26 | 5' 10" | 197 | Oregon State | KC | 15 03 098 | 5 |
| 45 | Nix, Roosevelt | FB | 03/30/1992 | 27 | 5' 11" | 265 | Kent State | ATL FA | 14 CFA | 5 |
| 76 | Okorafor, Chukwuma | OT | 08/08/1997 | 22 | 6' 06" | 320 | Western Michigan | PIT | 18 03 092 | 2 |
| 53 | Pouncey, Maurkice | OC | 07/24/1989 | 30 | 6' 04" | 304 | Florida | PIT | 10 01 018 | 10 |
| 2 | Rudolph, Mason | QB | 07/17/1995 | 24 | 6' 05" | 235 | Oklahoma State | PIT | 18 03 076 | 2 |
| 38 | Samuels, Jaylen | FB | 07/20/1996 | 23 | 5' 11" | 225 | North Carolina St | PIT | 18 05 165 | 2 |
| 19 | Smith-Schuster, JuJu | WR | 11/22/1996 | 22 | 6' 01" | 215 | USC | PIT | 17 02 062 | 3 |
| 24 | Snell Jr., Benny | RB | 02/27/1998 | 21 | 5' 10" | 224 | Kentucky | PIT | 19 04 122 | R |
| 20 | Sutton, Cameron | CB | 02/27/1995 | 24 | 5' 11" | 188 | Tennessee | PIT | 17 03 094 | 3 |
| 10 | Switzer, Ryan | WR | 11/04/1994 | 24 | 5' 08" | 179 | North Carolina | DAL | 17 04 133 | 3 |
| 91 | Tuitt, Stephon | DE | 05/23/1993 | 26 | 6' 05" | 304 | Notre Dame | PIT | 14 02 046 | 6 |
| 78 | Villanueva, Alejandro | OT/DE | 09/22/1988 | 31 | 6' 09" | 277 | Army | PHI FA | 14 SFA | 5 |
| 13 | Washington, James | WR | 04/02/1996 | 23 | 5' 11" | 213 | Oklahoma State | PIT | 18 02 060 | 2 |
| 90 | Watt, TJ | OB | 10/11/1994 | 24 | 6' 04" | 252 | Wisconsin | PIT | 17 01 030 | 3 |
| 98 | Williams, Vince | ILB | 12/27/1989 | 29 | 6' 01" | 233 | Florida State | PIT | 13 06 206 | 7 |
| Practice Squad |
| 27 | Allen, Marcus | FS | 08/07/1996 | 23 | 6' 02" | 215 | Penn State | PIT | 18 05 148 | 2 |
| 33 | Edmunds, Trey | TE | 12/30/1994 | 24 | 6' 02" | 227 | Maryland | NO FA | 17 CFA | 2 |
| 77 | Gray, Derwin | OT | 05/10/1995 | 24 | 6' 05" | 336 | Maryland | PIT | 19 07 219 | R |
| 14 | Jones, Tevin | WR | 12/26/1992 | 26 | 6' 02" | 218 | Memphis | HOU FA | 16 CFA | 1 |
| 5 | Lynch, Paxton | QB | 02/12/1994 | 25 | 6' 07" | 244 | Memphis | DEN | 16 01 026 | 3 |
| 35 | Mathis, Trevon | CB | 09/12/1995 | 24 | 6' 00" | 174 | Toledo | MIN FA | 18 CFA | 1 |
| 99 | Mondeaux, Henry | DT | 09/19/1995 | 24 | 6' 04" | 286 | Oregon | NO FA | 18 CFA | 1 |
| 62 | Morris, Patrick | OG | 02/13/1995 | 24 | 6' 02" | 293 | TCU | PIT FA | 18 CFA | 1 |
| 87 | Rader, Kevin | TE | 04/26/1995 | 24 | 6' 04" | 250 | Youngstown State | GB FA | 18 CFA | 1 |
| 49 | Scotland-Williamson, Christian | TE | 07/05/1993 | 26 | 6' 09" | 276 | No College | PIT FA | 18 CFA | 1 |
| 41 | Spillane, Robert | LB | 12/14/1995 | 23 | 6' 02" | 220 | Western Michigan | TEN FA | 18 CFA | 1 |
| Reserves |
| 21 | Davis, Sean | FS | 10/23/1993 | 25 | 6' 01" | 201 | Maryland | PIT | 16 02 058 | 4 |
| 95 | Hooks, Lavon | DT | 01/23/1992 | 27 | 6' 03" | 310 | Mississippi | GB FA | 15 CFA | 1 |
| 7 | Roethlisberger, Ben | QB | 03/02/1982 | 37 | 6' 05" | 241 | Miami University | PIT | 04 01 011 | 16 |
| 50 | Shazier, Ryan | OB | 01/14/1992 | 27 | 6' 01" | 237 | Ohio State | PIT | 14 01 015 | 6 |