| 1 | Sat, Aug 29 | vs  TCU | W 15-10 | Aviva Stadium
Dublin, IE_L |
| 1 | Sat, Sep 05 | Open Date | |
|
| 2 | Sat, Sep 12 | vs East Tennessee State | W 35-3 | Kenan Stadium
Chapel Hill, NC |
| 3 | Sat, Sep 19 | @  Clemson | L 20-28 | Memorial Stadium
Clemson, SC |
| 4 | Sat, Sep 26 | Open Date | |
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| 5 | Sat, Oct 03 | vs  3 Notre Dame | L 26-37 | Kenan Stadium
Chapel Hill, NC |
| 6 | Sat, Oct 10 | @  Pittsburgh | | Acrisure Stadium
Pittsburgh, PA |
| 7 | Sat, Oct 17 | @  Duke | | Wallace Wade Stadium
Durham, NC |
| 8 | Sat, Oct 24 | vs  Syracuse | | Kenan Stadium
Chapel Hill, NC |
| 9 | Sat, Oct 31 | vs  4 Miami | | Kenan Stadium
Chapel Hill, NC |
| 10 | Sat, Nov 07 | @  Connecticut | | Pratt & Whitney Stadium at Rentschler Field
Hartford, CT |
| 11 | Sat, Nov 14 | vs  Louisville | | Kenan Stadium
Chapel Hill, NC |
| 12 | Sat, Nov 21 | @  Virginia | | David A. Harrison III Field at Scott Stadium
Charlottesville, VA |
| 13 | Sat, Nov 28 | vs  North Carolina St | | Kenan Stadium
Chapel Hill, NC |
| 14 | Sat, Dec 05 | Open Date | |
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