| Pick | Team | Player | Pos. | School |
| Round 1 |
| 1 |
Chiefs
| Luke Joeckel | OT | Texas A&M |
| Need to protect Alex Smith |
| 2 |
Jaguars
| Jarvis Jones | OB | Georgia |
| 3 |
Raiders
| Sharrif Floyd | DT | Florida |
| 4 |
Eagles
| Dee Milliner | DC | Alabama |
| 5 |
Lions
| Bjoern Werner | DE | Florida State |
| 6 |
Browns
| Cordarrelle Patterson | WR | Tennessee |
| 7 |
Cardinals
| Geno Smith | QB | West Virginia |
| 8 |
Bills
| Matt Barkley | QB | Southern Cal |
| 9 |
Jets
| Eddie Lacy | RB | Alabama |
| 10 |
Titans
| Chance Warmack | OG | Alabama |
| 11 |
Chargers
| Elvis Fisher | OT | Missouri |
| 12 |
Dolphins
| Star Lotulelei | DT | Utah |
| 13 |
Jets
F/TB
| Xavier Rhodes | DC | Florida State |
| 14 |
Panthers
| Lane Johnson | OT | Oklahoma |
| 15 |
Saints
| Barkevious Mingo | OB | LSU |
| 16 |
Rams
| Jonathan Cooper | OG | North Carolina |
| 17 |
Steelers
| Tavon Austin | WR | West Virginia |
| 18 |
Cowboys
| Kenny Vaccaro | FS | Texas |
| 19 |
Giants
| DJ Fluker | OT | Alabama |
| 20 |
Bears
| Alec Ogletree | IB | Georgia |
| 21 |
Bengals
| Giovani Bernard | RB | North Carolina |
| 22 |
Rams
F/WAS
| Keenan Allen | WR | California |
| 23 |
Vikings
| Robert Woods | WR | Southern Cal |
| 24 |
Colts
| DeAndre Hopkins | WR | Clemson |
| 25 |
Vikings
F/SEA
| Desmond Trufant | DC | Washington |
| 26 |
Packers
| Dion Jordan | DE | Oregon |
| 27 |
Texans
| Matt Elam | SS | Florida |
| 28 |
Broncos
| Ezekiel Ansah | DE | BYU |
| 29 |
Patriots
| Kyle Long | OT | Oregon |
| 30 |
Falcons
| Sheldon Richardson | DT | Missouri |
| 31 |
49ers
| Barrett Jones | OC | Alabama |
| 32 |
Ravens
| Tyler Eifert | TE | Notre Dame |