| Pick | Team | Player | Pos. | School |
| Round 1 |
| 1 |
Jaguars
| Trevor Lawrence | QB | Clemson |
| 2 |
Jets
| Zach Wilson | QB | BYU |
| 3 |
49ers
f/MIA/HOU
| Mac Jones | QB | Alabama |
| 4 |
Falcons
| Kyle Pitts | TE | Florida |
| 5 |
Bengals
| Rashawn Slater | OT | Northwestern |
| 6 |
Dolphins
f/PHI
| Ja'Marr Chase | WR | LSU |
| 7 |
Lions
| Jaylen Waddle | WR | Alabama |
| TRADE - Detroit trades pick #7 to the NY Giants for pick #11. |
| 8 |
Panthers
| Penei Sewell | OT | Oregon |
| 9 |
Broncos
| Trey Lance | QB | North Dakota State |
| 10 |
Cowboys
| Justin Fields | QB | Ohio State |
| TRADE - Dallas trades pick #10 to New England for pick #15. |
| 11 |
Giants
| Micah Parsons | IB | Penn State |
| TRADE - The NY Giants trade pick #11 to Detroit for pick #7. |
| 12 |
Eagles
f/MIA/SF
| DeVonta Smith | WR | Alabama |
| 13 |
Chargers
| Jaycee Horn | CB | South Carolina |
| 14 |
Vikings
| Christian Darrisaw | OT | Virginia Tech |
| 15 |
Patriots
| Christian Barmore | DT | Alabama |
| TRADE - New England trades pick #15 to Dallas for pick #10. |
| 16 |
Cardinals
| Patrick Surtain II | CB | Alabama |
| 17 |
Raiders
| Jeremiah Owusu-Koramoah | OB | Notre Dame |
| 18 |
Dolphins
| Zaven Collins | IB | Tulsa |
| 19 |
Football Team
| Trevon Moehrig | FS | TCU |
| 20 |
Bears
| Azeez Ojulari | OB | Georgia |
| 21 |
Colts
| Teven Jenkins | OT | Oklahoma State |
| 22 |
Titans
| Greg Newsome | CB | Northwestern |
| 23 |
Jets
f/SEA
| Jaelan Phillips | DE | Miami |
| 24 |
Steelers
| Alijah Vera-Tucker | OG | Southern Cal |
| 25 |
Jaguars
f/LAR
| Kwity Paye | DE | Michigan |
| 26 |
Browns
| Caleb Farley | CB | Virginia Tech |
| 27 |
Ravens
| Jayson Oweh | DE | Penn State |
| 28 |
Saints
| Rondale Moore | WR | Purdue |
| 29 |
Packers
| Rashod Bateman | WR | Minnesota |
| 30 |
Bills
| Asante Samuel Jr. | CB | Florida State |
| 31 |
Ravens
f/KC
| Elijah Moore | WR | Mississippi |
| 32 |
Buccaneers
| Najee Harris | RB | Alabama |
| Round 2 |
| 33 |
Jaguars
| Kadarius Toney | WR | Florida |
| 34 |
Jets
| Samuel Cosmi | OT | Texas |
| 35 |
Falcons
| Gregory Rousseau | DE | Miami |
| 37 |
Eagles
| Carlos Basham Jr. | DE | Wake Forest |
| 39 |
Panthers
| Dyami Brown | WR | North Carolina |
| 40 |
Broncos
| Nick Bolton | OB | Missouri |
| 41 |
Lions
| Elijah Molden | SS | Washington |
| 42 |
Giants
| Landon Dickerson | OC | Alabama |
| 43 |
49ers
| Eric Stokes | CB | Georgia |
| 47 |
Chargers
| Dillon Radunz | OT | North Dakota State |
| 51 |
Football Team
| Kyle Trask | QB | Florida |
| 54 |
Colts
| Ronnie Perkins | DE | Oklahoma |
| 55 |
Steelers
| Travis Etienne | RB | Clemson |
| 56 |
Seahawks
| Tylan Wallace | WR | Oklahoma State |
| 57 |
Rams
| Quintin Meinerz | OG | Wisconsin-Whitewater |
| Round 3 |
| 65 |
Jaguars
| Walker Little | OT | Stanford |
| 72 |
Lions
| Tommy Togiai | DT | Ohio State |
| 74 |
Football Team
f/SF
| Brevin Jordan | TE | Miami |
| 87 |
Steelers
| Creed Humphrey | OC | Oklahoma |
| 88 |
Rams
| Alim McNeill | DT | North Carolina State |
| 96 |
Patriots
f/NFL
| Kellen Mond | QB | Texas A&M |
| 101 |
Lions
F/LAR
| Josh Myers | OC | Ohio State |
| 103 |
Rams
F/NFL
| Thomas Graham Jr. | CB | Oregon |
| Round 4 |
| 112 |
Lions
| Anthony Schwartz | WR | Auburn |
| 125 |
Vikings
f/CHI
| Chauncey Golston | DE | Iowa |
| 127 |
Colts
| Tommy Tremble | TE | Notre Dame |
| 128 |
Steelers
| Jack Anderson | OG | Texas Tech |
| 129 |
Seahawks
| Trill Williams | FS | Syracuse |
| 134 |
Vikings
f/BUF
| Marlon Tuipulotu | NT | Southern Cal |
| 140 |
Steelers
F/NFL
| John Bates | TE | Boise State |
| 141 |
Rams
F/NFL
| Demetric Felton | RB | UCLA |
| Round 5 |
| 153 |
Lions
| Brenden Jaimes | OT | Nebraska |
| 157 |
Vikings
| Kylin Hill | RB | Mississippi State |
| 160 |
Cardinals
| Jaylen Twyman | DT | Pittsburgh |
| 165 |
Colts
| Deommodore Lenoir | CB | Oregon |
| 168 |
Vikings
f/PIT/BAL
| Feleipe Franks | QB | Arkansas |
| Round 6 |
| 194 |
49ers
| Avery Williams | CB | Boise State |
| 199 |
Vikings
| Derrick Barnes | LB | Purdue |
| 206 |
Colts
| Frank Darby | WR | Arizona State |
| 209 |
Rams
| Darren Hall | CB | San Diego State |
| 216 |
Steelers
f/TB
| Garret Wallow | IB | TCU |
| 223 |
Vikings
F/NFL
| Kenny Yeboah | TE | Mississippi |
| Round 7 |
| 243 |
Cardinals
| Carson Green | OT | Texas A&M |
| 247 |
Cardinals
f/CHI/LV
| Jacob Harris | WR | Central Florida |
| 248 |
Colts
| Jordyn Peters | SS | Auburn |
| 250 |
Seahawks
| Darius Stills | DT | West Virginia |
| 252 |
Rams
| Erroll Thompson | IB | Mississippi State |